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Characterization of nanosecond micro-mixers
S. Mitic1, J. van Nieuwkasteele2, A. van den Berg2, S. de Vries1 . 1Section Enzymology – Department of Biotechnology – Delft University of Technology, Julianalaan 67, 2628 BC Delft, The Netherlands; 2MESA+ Research Institute - University of Twente, 7500 AE Enschede,

We have constructed two four-jet-tangential micro-mixers, one from stainless-steel to study reactions in a freeze-quench setup, instrumental-dead-time 60µs and one from glass allowing optical studies. Both mixers contain 70µm channels ending in premixing-chamber. After the premixing-chamber, the fluids enter a mixing-chamber and leaves at an orifice travelling further as a free jet, mixing-time 200 ns, jet flow 200 m/s, pressure 400 bar.

Modular Glass Chip System for the Acquisition of the Electric Activity and Physiological Parameters of Differentiated Stem Cells
P. J. Koester, J. Sakowski, S. M. Buehler, C. Tautorat, H. Altrichter, W. Baumann and J. Gimsa. University of Rostock

The EU chemical policy REACH, effective on June 2007, regulates the registration, evaluation and authorization of chemicals. Investigations on the effects of neurotoxic and developmental-neurotoxic substances are required by European and US-American test guidelines. However, at the moment these tests are based on animal experiments contradicting society claims to abolish animal experiments and to implement the 3R-principle. The resulting problem is… How to pair REACH and the 3Rs?

Development of a Lab-on-a-Chip for the Characterization of Human Cells
Richter, L., Stepper, C., Mak, A., Brückl, H. and Ertl, P.. ARC and Nano-Systemtechnologies

Cell chips are developed to continuously monitor mammalian cell population dynamics in a non-invasive manner. In the presented work we describe the design, fabrication and characterization of a lab-on-a-chip for quantitative cell analysis.

A Novel Ultrasonic Method for Characterizing Suspensions of Nanoparticles
Steven Africk and Clark K. Colton. Prodyne Corp., and MIT

The UltraSonic Pulsed Doppler technique is a novel ultrasonic-backscatter technique for characterizing nanoparticles. Using a single transducer and able to operate in almost arbitrary vessels on samples over a range of concentrations and opacities, the system can measure concentration, size (with precision exceeding that of DLS) and mechanical compliance (for particle functionalization monitoring). To date, the system has ‘imaged’ dendrimers, colloids, carbon nanotubes, polymer beads and protein

The Regulated Gas Medium with a Set of Nanoparticles Generated by the Solid Fuel Composition as a Method for Producing Ecovegetables
Alexandre V. Vakhrouchev and Valery B. Golubchikov. Izhevsk State University, Ltd. “Nord”

New biotechnology involving nanoparticles for the production of ecologically pure vegetables in greenhouses has described. The main feature of the method is the generation of a special controlled gas medium containing nanoparticles of the main macro- and microelements, which freely penetrate into the foliage and stems of crops providing their metabolic activity. The source of the gas medium is the products of self-spreading high-temperature synthesis.

Gold Coated Magnetic Nanoparticles for Specific Separation and Detection of Oligonucleotide Sequences and Proteins
Pedro Quaresma, Ricardo Franco, Pedro Baptista, Patricia Carvalho and Eulalia Pereira. Universidade Nova de Lisboa, Universidade do Porto and Universidade Techica de Lisboa

Monodisperse magnetic nanoparticles were produced and subsequently coated with a gold layer by the reduction at surface of a gold precursor in order to develop an integrated detection and “gene fishing” system. Functionalization of the nanoparticles could allow the application of this system to a variety of biomolecules.

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