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Designing the photon electron converter in modified PEEM by Monte Carlo method
Nghia T. Vo, Ekkehard Pomplun, Eberhard Kümmerle, Herbert O. Moser. Singapore Synchrotron Light Source, National University of Singapore (NUS))
This work shows how we can design a photocathode (photon electron converter) by using Monte Carlo simulation method
A Practical Microfluidic Device for Synthesis of Purified Monodisperse Micro-Alginate Beads (MABs) as Microcarriers of Gold Nanoparticles.
Paul-Emile POLENI, Serge OSTROVIDOV, Yasuyuki SAKAI and Teruo FUJII. Institute of Industrial Science, The University of Tokyo
We developed a microfluidic device for encapsulating gold nanoparticles in Micro-Alginate Beads (MABs). The size and the gap of the monodisperse alginate droplets were successfully controlled by adjusting the relative "oil/sample" flow rate ratio. Droplets reacted with calcium ion at the interface between oil phase and aqueous phase so that MABs precipitated spontaneously and undergone complete gelation. Purified MABs were successfully observed by fluorescence microscopy.
Hyaluronan-Chitosan Polyelectrolytic Complex as a Platform for Delivery of Cytotoxic Agents
Philen S, Coleman R, Gilbert A, McFadden K, Sharma, S, Stensgard E, Brekke, JH and Rutkowski GE. University of Minnesota Duluth. Dept Chemical Engineering
Described here is a biomimetic hydrogel adapted to serve as a high concentration, regional delivery system for cytotoxic agents. Paclitaxel was conjugated with low molecular weight hyaluronan to render it water soluble, then embedded in the HCP-h hydrogel for delivey to a culture of C8161 malignant melanoma cells. Live/dead staining of cells was used to monitor effectiveness of paclitaxel release from its HCP-h depot.
Fabrication and characterization of a fully integrated microdevice for in-vitro single cell assays
C. Collini, E. Morganti, R. Cunaccia, L. Odorizzi, C. Ress, and L. Lorenzelli (1), A. De Toni, G. Marinaro (2), M. Borgo (3), M. Maschietto (4). (1) FBK-BIOMEMS Unit, via Sommarive 18, 38123 Povo – TN – Italy, (2)Dipartimento di Ingegneria dell’informazione –University of Padova – 35131 Padova – Italy, (3) BioSiLab, 38068 Rovereto – TN – Italy
This work presents the microfabrication and preliminary characterization of a fully integrated microdevice for in-vitro single cell assays. This technological platform combines IDEs and MEA-based modules for cell addressed delivery of bio-functionalized nano/microparticles and single cell electroporation respectively.
The Hind Sight of Nanotechnology
Suman Lahiri, Mamta Shah. L M College of Pharmacy
Nanotechnology addresses manipulation and study of structures and devices with length scales in the 1- to 100-nanometers range. Market growing upto 1 to 2.95 trillion $ by 2015, projects nanotubes to cross US$5 billion by the year 2012. In view of the toxicity that can be posed by it serious problems can threaten to neutralize the gains of nanotechnology.
Experimental Determination of ADMET Parameters in High Throughput, Using Colloidal Gold Composites and a Conductive Polymer as Reporting Reagents
Roberto Martinez-Neira, Patricia De Pril, Anne Van Hoonacker, Patrick Englebienne. Pharmadiagnostics N.V.
We developed and validated a high throughput in vitro setting to experimentally determine hSA and Orosomucoid affinities, fraction absorbed, Log BBB and Redox potential of NCEs using gold nanoparticles functionalized with proteins, lipids or conductive polymers. Such automated ADME assays provide means for more objective decisions in early drug discovery.
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